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Table 1 G894 T eNOS distribution Vs Clinical parameters

From: The polymorphism G894 T of endothelial nitric oxide synthase (eNOS) gene is associated with susceptibility to essential hypertension (EH) in Morocco

  eNOS P value (< 0.05)
GG % GT % TT %  
Age 58.6 ± 9.34 61.77 ± 10.1 60.87 ± 10.25 0.07
Gender     0.4
 ♀ 2.6 39.7 57.7  
 ♂ 6.9 34.5 58.6  
Ethnicity     0.5
 White 4.5 41 54.5  
 Metis 3.4 34.8 61.8  
 Black 0 58.3 41.7  
Familial History of EH     0.5
 yes 4.5 39.8 55.7  
 no 1.8 36.8 61.4  
Familial History of CVD     0.6
 yes 5.9 38.2 55.9  
 no 2.7 38.7 58.6  
Familial History of Cerebrovascular disease     0.9
 yes 2.6 36.9 60.5  
 no 3.7 39.3 57  
Familial History of Diabetes     0.3
 yes 3.8 43.6 52.6  
 no 3 32.8 64.2  
Familial History of Renal disease     0.8
 yes 0 40 60  
 no 3.7 38.5 57.8  
Familial History of Dyslipidemia     0.3
 yes 4.7 30.2 65.1  
 no 2.9 42.2 54.9  
Smoking     0.2
 yes 7.7 53.8 38.5  
 no 3 37.1 59.9  
Alcohol     0.009*
 yes 25 75 0  
 no 2.8 37.6 59.6  
Physical Activity     0.05
 yes 7.1 35.7 57.1  
 no 0 41.3 58.7  
Obesity     0.02*
 yes 6.5 27.4 66.1  
 no 1.2 47 51.8  
Dyslipidemia     0.9
 yes 3.4 37.9 58.6  
 no 3.4 39.1 57.5  
Diabetes     0.9
 yes 3.8 37.7 58.5  
 no 3.3 39.1 57.6  
Menopausal status     0.2
 yes 3 32.8 64.2  
 no 2 48 50  
Personal History of CVD     0.07
 yes 9.7 29 61.3  
 no 1.9 42.9 55.2  
Nephropathy     0.8
 yes 0 33.3 66.7  
 no 3.6 38.8 57.6  
Nbr of antihypertensive molecules     0.7
 1 3.1 37.5 59.4  
 2 5.1 42.3 52.6  
 3 0 36 64  
 4 0 22.2 77.8  
TA     0.7
 controled 4.3 37.2 58.5  
 non-controled 2 41.2 56.8  
Neurological deficit     0.7
 yes 0 33.3 66.7  
 no 3.7 39 57.3  
Electrical HVG     0.7
 yes 0 38.5 61.5  
 no 3.8 38.6 57.6  
Repolarisation troubles     0.5
 yes 5.8 47.1 47.1  
 no 3.1 37.5 59.4  
Creatinine 7.9 ± 4.14 11.38 ± 6.21   0.2
 TG     0.5
  ≤ 1 4.5 41 54.5  
  >  1 2.4 31.3 66.3  
 CT     0.3
  ≤ 1 0 0 3  
  >  1 2.8 36.7 60.6  
 HDL     0.8
  ≤ 0.5 2 36 62.8  
  >  0.5 3.8 32.1 64.2  
 LDL     0.9
  ≤ 0.5 0 0 100  
  >  0.5 3 31 66  
 Glucose 1.02 ± 0.48 1.18 ± 0.56 1.32 ± 0.6 0.9
  Na+ 137 ± 28 139.6 ± 34.9 135.3 ± 20.6 0.3
  K+ 4.1 ± 1.8 4.06 ± 1.9 4.22 ± 1.8 0.3
  1. *Statistically significant; Nbr number, HVG left ventricular hypertrophy, GG Homozygous wild type, GT Heterozygous, TT Homozygous mutant
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