Fig. 1

Scheme of the gene encoding endothelial nitric oxide synthase gene (eNOS) (a and b) [18]. Scheme of the gene encoding endothelial nitric oxide synthase (eNOS or NOS3). The human NOS3 gene (located at 7q35-36) contains 26 exons that span 21 kb. Exons are described by number. AUG: the transcription start site. Three specific polymorphisms in the NOS3 gene are marked by arrows. c Scheme of the eNOS protein