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Table 3 The association results of two SNPs in DSCAM to different subclinical features classified by aganglionois length including short-length (S-HSCR), long-length (L-HSCR) and TCA

From: Association between DSCAM polymorphisms and non-syndromic Hirschsprung disease in Chinese population

Length of Aganglionosis CHR SNP BP A1/A2 F_A F_U P OR CI 0.95
SHSCR 21 rs2837770 40,662,426 G/A 0.59 0.54 3.06E-03 1.21 (1.07~ 1.38)
21 rs8134673 40,676,385 G/A 0.59 0.54 3.33E-03 1.21 (1.07~ 1.38)
LHSCR 21 rs2837770 40,662,426 G/A 0.56 0.54 0.63 1.05 (0.86~ 1.27)
21 rs8134673 40,676,385 G/A 0.54 0.54 0.91 1.01 (0.84~ 1.22)
TCA 21 rs2837770 40,662,426 G/A 0.56 0.54 0.66 1.07 (0.78~ 1.48)
21 rs8134673 40,676,385 G/A 0.57 0.54 0.2 1.12 (0.81~ 1.55)
  1. CHR Chromosome, SNP Single Nucleotide Polymorphism, BP Base pair of where the SNP is located. A1/A2 indicates the risk allele and protective allele to disease; F_A/F_U indicates risk allele frequency of the SNP in cases or controls. The P value indicates the significance based on allelic association tests. The calculation of odds ratio (OR) is also based on the risk allele of each SNP