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Table 2 Association analyses of the FCRL3 –169T>C and FOXP3 –2383C>T polymorphisms in tendinopathy cases compared with controls

From: Fc receptor-like 3 (−169T>C) polymorphism increases the risk of tendinopathy in volleyball athletes: a case control study

SNP

Controls

n (%)

Tendinopathy

p-valuea

OR (95% CI)b

FCRL3 -169T>C

(n = 123)

(n = 142)

  

TT

48 (39.0)

40 (28.2)

 

1c

TC

56 (45.6)

70 (49.3)

0.19

1.50 (0.86–2.59)

CC

19 (15.4)

32 (22.5)

0.04

2.02 (0.10–4.09)

TC + CC

75 (61.0)

102 (71.8)

0.08

1.63 (0.97–2.73)

T

152 (61.8)

150 (52.8)

0.04

1c

C

94 (38.2)

134 (47.2)

1.44 (1.02–2.04)

FOXP3 -2383C>T

(n = 123)

(n = 138)

  

CC

86 (69.9)

97 (70.3)

 

1c

CT

30 (24.4)

37 (26.8)

0.86

1.09 (0.62–1.92)

TT

7 (5.7)

4 (2.9)

0.45

0.51 (0.14–1.79)

CT + TT

37 (30.1)

41 (29.7)

1.0

0.98 (0.58–1.67)

C

202 (82.1)

231 (83.7)

0.71

1c

T

44 (17.9)

45 (16.3)

0.89 (0.57–1.41)

  1. Note: SNP single nucleotide polymorphism, OR odds ratio, CI confidence interval
  2. aChi-Square Test or Fisher’s exact test
  3. bAdjusted by age, years of practice in volleyball, gender and pain
  4. cReference group