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Table 6 Association between Alleles and median EFS rate in osteosarcoma patients treated with cisplatin combinations

From: The effect of ERCC1 and ERCC2 gene polymorphysims on response to cisplatin based therapy in osteosarcoma patients

Alleles Median EFS survival rate in years Log rank
ERCC1 118 C allele CC + CT 1.70 0.549
TT 1.73
ERCC1 118 T allele TT + CT 1.49 0.647
CC 2.29
ERCC1 8092 C allele CC + CA 2.04 0.006
AA 0.24
ERCC1 8092 A allele AA+CA 2.04 0.879
CC 1.42
ERCC2 312 G allele GG + GA 2.04 0.084
AA 1.17
ERCC2 312 A allele AA+GA 2.04 0.511
GG 1.42
ERCC2 751 A allele AA+AC 1.80 0.287
CC not reached
ERCC2 751 C allele CC + AC 3.07 0.181
AA 1.42