Table 1 Clinical characteristics of the discovery cohort (GENRES) and replication cohorts (DYNAMIC and DILGOM)
From: Genome-wide association study of nocturnal blood pressure dipping in hypertensive patients
Variables | GENRES | DYNAMIC | DILGOM |
|---|---|---|---|
n | 204 | 183 | 180 |
Age (years) | 50.7 ± 6.3 | 47.5 ± 11.7 | 56.3 ± 11.4 |
Men (%) | 100 | 60 | 47 |
Body Mass Index (kg/m2) | 26.4 ± 2.7 | 27.1 ± 4.2 | 26.6 ± 4.4 |
Waist-hip ratio | 0.99 ± 0.05 | 0.91 ± 0.08 | 0.91 ± 0.09 |
Current smokers (%) | 15.7 | 15.3 | 7.8 |
Blood pressure levels (mmHg) | |||
Office measurements | |||
SBP | 152 ± 13 | 145 ± 18 | 129 ± 18 |
DBP | 100 ± 7 | 92 ± 12 | 79 ± 10 |
Ambulatory recordings | |||
Daytime | |||
SBP | 144 ± 10 | 140 ± 13 | 128 ± 12 |
DBP | 99 ± 6 | 88 ± 8 | 78 ± 8 |
Nighttime | |||
SBP | 118 ± 11 | 118 ± 13 | 112 ± 12 |
DBP | 81 ± 6 | 71 ± 9 | 65 ± 8 |
Nocturnal dipping | |||
Night-to-day BP ratio (%) | |||
SBP | 81.9 ± 5.3 | 84.2 ± 5.7 | 87.8 ± 6.2 |
DBP | 81.9 ± 4.8 | 80.4 ± 6.4 | 83.7 ± 8.1 |
Percentage of non-dippers (%) | |||
7 | 16 | 32 | |