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Table 1 Clinical characteristics of the discovery cohort (GENRES) and replication cohorts (DYNAMIC and DILGOM)

From: Genome-wide association study of nocturnal blood pressure dipping in hypertensive patients

Variables GENRES DYNAMIC DILGOM
n 204 183 180
Age (years) 50.7 ± 6.3 47.5 ± 11.7 56.3 ± 11.4
Men (%) 100 60 47
Body Mass Index (kg/m2) 26.4 ± 2.7 27.1 ± 4.2 26.6 ± 4.4
Waist-hip ratio 0.99 ± 0.05 0.91 ± 0.08 0.91 ± 0.09
Current smokers (%) 15.7 15.3 7.8
Blood pressure levels (mmHg)
 Office measurements
   SBP 152 ± 13 145 ± 18 129 ± 18
   DBP 100 ± 7 92 ± 12 79 ± 10
 Ambulatory recordings
  Daytime
   SBP 144 ± 10 140 ± 13 128 ± 12
   DBP 99 ± 6 88 ± 8 78 ± 8
  Nighttime
   SBP 118 ± 11 118 ± 13 112 ± 12
   DBP 81 ± 6 71 ± 9 65 ± 8
Nocturnal dipping
 Night-to-day BP ratio (%)
   SBP 81.9 ± 5.3 84.2 ± 5.7 87.8 ± 6.2
   DBP 81.9 ± 4.8 80.4 ± 6.4 83.7 ± 8.1
 Percentage of non-dippers (%)
  7 16 32
  1. Non-dipper is defined as night-to-day BP ratio > 90% for either systolic or diastolic blood pressure dipping. Values are presented as mean mean ± standard deviation. Abbreviations: SBP systolic blood pressure, DBP diastolic blood pressure, BP blood pressure