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Table 3 Characteristics of studies evaluating the effects of GSTM1 and GSTT1 null genotypes on clinical TNM stages of RCC

From: A systematic review and meta-analyses of the relationship between glutathione S-transferase gene polymorphisms and renal cell carcinoma susceptibility

Gene Author, Year Country Ethnicity Source of controls Quality Stage I + II Stage III + IV
Locus Score + Total + Total
GSTM1-TNM Sweeney 2000 USA Mix Population-based 9 50 55 105 15 8 23
De Martino 2010 Austria Caucasian Hospital-based 8 45 29 74 35 38 73
Ahmad 2012 India Asian Population-based 11 53 77 130 49 17 66
Abid 2016 Pakistan Asian Hospital-based 8 77 115 192 93 168 261
GSTT1-TNM Sweeney 2000 USA Mix Population-based 9 29 76 105 6 17 23
De Martino 2010 Austria Caucasian Hospital-based 8 12 62 74 15 58 73
Ahmad 2012 India Asian Population-based 11 72 58 130 53 13 66
Salinas-Sanchez 2012 Spain Caucasian Hospital-based 6 39 40 79 25 11 36
Abid 2016 Pakistan Asian Hospital-based 8 21 161 182 36 200 236