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Table 1 Characteristics of studies evaluating the effects of GSTM1 and GSTT1 null genotypes on RCC risk

From: A systematic review and meta-analyses of the relationship between glutathione S-transferase gene polymorphisms and renal cell carcinoma susceptibility

Gene

Author, Year

Country

Ethnicity

Source of controls

Quality

Case

Control

Locus

    

Score

–

+

Total

–

+

Total

GSTM1

Bruning 1997

Germany

Caucasian

Population-based

6

18

27

45

31

17

48

Longuemaux 1999

France

Caucasian

Hospital-based

8

89

84

173

117

94

211

Sweeney 2000

USA

Mix

Population-based

9

63

63

126

255

250

505

Buzio 2003

Italy

Caucasian

Hospital-based

8

50

50

100

108

92

200

Moore 2007

Europe

Caucasian

Hospital-based

9

424

487

911

555

677

1232

Wiesenhütter 2007

Germany

Caucasian

Hospital-based

8

51

47

98

167

157

324

Karami 2008

Europe

Caucasian

Hospital-based

9

303

321

624

433

454

887

Coric 2010

Serbia

Caucasian

Hospital-based

8

46

30

76

86

96

182

De Martino 2010

Austria

Caucasian

Hospital-based

8

80

67

147

59

53

112

Ahmad 2012

India

Asian

Population-based

11

102

94

196

116

134

250

Salinas-Sanchez 2012

Spain

Caucasian

Hospital-based

6

57

76

133

78

115

193

Jia 2014

China

Asian

Population-based

NC

22

28

50

30

30

60

Coric 2016

Serbia

Caucasian

Hospital-based

8

87

109

196

137

137

274

Abid 2016

Pakistan

Asian

Hospital-based

8

224

378

602

171

248

419

Coric 2017

Serbia

Caucasian

Hospital-based

8

169

136

305

163

163

326

GSTT1

Bruning 1997

Germany

Caucasian

Population-based

6

3

42

45

11

37

48

Longuemaux 1999

France

Caucasian

Hospital-based

8

25

148

173

40

171

211

Sweeney 2000

USA

Mix

Population-based

9

36

90

126

93

412

505

Buzio 2003

Italy

Caucasian

Hospital-based

8

11

89

100

35

165

200

Moore 2007

Europe

Caucasian

Hospital-based

9

167

744

911

209

1023

1232

Wiesenhütter 2007

Germany

Caucasian

Hospital-based

8

19

79

98

59

265

324

Karami 2008

Europe

Caucasian

Hospital-based

9

129

499

628

161

752

913

Coric 2010

Serbia

Caucasian

Hospital-based

8

21

55

76

52

130

182

De Martino 2010

Austria

Caucasian

Hospital-based

8

27

120

147

23

89

112

Salinas-Sanchez 2012

Spain

Caucasian

Hospital-based

6

22

110

132

25

138

163

Ahmad 2012

India

Asian

Population-based

11

125

71

196

106

144

250

Jia 2014

China

Asian

Population-based

NC

30

18

48

25

35

60

Coric 2016

Serbia

Caucasian

Hospital-based

8

44

152

196

71

203

274

Abid 2016

Pakistan

Asian

Hospital-based

8

72

482

554

49

330

379

Coric 2017

Serbia

Caucasian

Hospital-based

8

79

226

305

89

237

326

GSTM1-GSTT1

Bruning 1997

Germany

Caucasian

Population-based

6

1

44

45

6

42

48

Sweeney 2000

USA

Mix

Population-based

9

17

109

126

49

456

505

Moore 2007

Europe

Caucasian

Hospital-based

9

82

829

911

99

1133

1232

Karami 2008

Europe

Caucasian

Hospital-based

9

363

260

623

508

372

880

Salinas-Sanchez 2012

Spain

Caucasian

Hospital-based

6

7

126

133

8

185

193

Ahmad 2012

India

Asian

Population-based

11

71

125

196

54

196

250

Jia 2014

China

Asian

Population-based

NC

14

34

48

10

50

60

Coric 2016

Serbia

Caucasian

Hospital-based

8

24

20

44

36

35

71

Abid 2016

Pakistan

Asian

Hospital-based

8

29

524

553

17

333

350

  1. NC not clear