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Table 1 Demographic, anthropometric, and clinical characteristics of the control and patient study groups

From: Impact of KCNQ1, CDKN2A/2B, CDKAL1, HHEX, MTNR1B, SLC30A8, TCF7L2, and UBE2E2 on risk of developing type 2 diabetes in Thai population

Clinical characteristics Controls (n = 500) Patients (n = 500) p-value
Gender (M, F) (%) 28.8, 71.2 32.8, 67.2 0.170164:336
Age (yrs) (years) 53.0 ± 8.4 57.2 ± 12.2 < 0.001 a
Age at diagnosis (yrs) 49.4 ± 11.3 ND
Weight (kg) 60.0 ± 10.0 67.7 ± 13.8 < 0.001 a
Waist circumference (cm) 83.3 ± 9.4 89.6 ± 11.4 < 0.001 a
Waist-to-hip ratio 0.8 ± 0.1 0.9 ± 0.1 < 0.001 a
BMI (kg/m2) 24.1 ± 3.3 27.3 ± 5.0 < 0.001 a
SBP (mmHg) 116.7 ± 15.4 134.9 ± 19.4 < 0.001 a
DBP (mmHg) 71.7 ± 10.3 79.3 ± 10.4 < 0.001 a
FPG (mmol/l) 3.9 (3.4, 4.4) 8.4 (6.6, 12.1) < 0.001 b
HbA1c (mmol/mol) 36.6 (34.2, 37.7) 57.4 (48.0, 74.9) < 0.001
TC (mmol/l) 208.4 ± 37.9 200.2 ± 53.3 < 0.001 a
TG (mmol/l) 2.3 (2.0, 2.6) 1.5 (1.1, 2.1) < 0.001 b
LDL-C (mmol/l) 2.5 (1.8, 3.5) 2.1 (1.2, 3.6) < 0.001 b
HDL-C (mmol/l) 3.2 (2.6, 3.9) 1.6 (1.1, 2.2) < 0.001 b
  1. Data presented as mean ± standard deviation or median and interquartile range
  2. A p-value< 0.05 indicates statistical significance
  3. Gender distribution between patients and controls was analyzed using Pearson’s χ2 test
  4. Comparison of quantitative variables between patients and controls was performed using Student’s t-test or Mann-Whitney U test
  5. ap-values and bp-values were determined using Student’s t-test and Mann-Whitney U test, respectively
  6. Abbreviations: M male, F female, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, FPG fasting plasma glucose, HbA 1c glycated hemoglobin, TC total cholesterol, TG triglycerides, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, ND not determined