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Table 1 Demographic, anthropometric, and clinical characteristics of the control and patient study groups

From: Impact of KCNQ1, CDKN2A/2B, CDKAL1, HHEX, MTNR1B, SLC30A8, TCF7L2, and UBE2E2 on risk of developing type 2 diabetes in Thai population

Clinical characteristics

Controls (n = 500)

Patients (n = 500)

p-value

Gender (M, F) (%)

28.8, 71.2

32.8, 67.2

0.170164:336

Age (yrs) (years)

53.0 ± 8.4

57.2 ± 12.2

< 0.001 a

Age at diagnosis (yrs)

–

49.4 ± 11.3

ND

Weight (kg)

60.0 ± 10.0

67.7 ± 13.8

< 0.001 a

Waist circumference (cm)

83.3 ± 9.4

89.6 ± 11.4

< 0.001 a

Waist-to-hip ratio

0.8 ± 0.1

0.9 ± 0.1

< 0.001 a

BMI (kg/m2)

24.1 ± 3.3

27.3 ± 5.0

< 0.001 a

SBP (mmHg)

116.7 ± 15.4

134.9 ± 19.4

< 0.001 a

DBP (mmHg)

71.7 ± 10.3

79.3 ± 10.4

< 0.001 a

FPG (mmol/l)

3.9 (3.4, 4.4)

8.4 (6.6, 12.1)

< 0.001 b

HbA1c (mmol/mol)

36.6 (34.2, 37.7)

57.4 (48.0, 74.9)

< 0.001

TC (mmol/l)

208.4 ± 37.9

200.2 ± 53.3

< 0.001 a

TG (mmol/l)

2.3 (2.0, 2.6)

1.5 (1.1, 2.1)

< 0.001 b

LDL-C (mmol/l)

2.5 (1.8, 3.5)

2.1 (1.2, 3.6)

< 0.001 b

HDL-C (mmol/l)

3.2 (2.6, 3.9)

1.6 (1.1, 2.2)

< 0.001 b

  1. Data presented as mean ± standard deviation or median and interquartile range
  2. A p-value< 0.05 indicates statistical significance
  3. Gender distribution between patients and controls was analyzed using Pearson’s χ2 test
  4. Comparison of quantitative variables between patients and controls was performed using Student’s t-test or Mann-Whitney U test
  5. ap-values and bp-values were determined using Student’s t-test and Mann-Whitney U test, respectively
  6. Abbreviations: M male, F female, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, FPG fasting plasma glucose, HbA 1c glycated hemoglobin, TC total cholesterol, TG triglycerides, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, ND not determined