Table 4 Comparison of ABCC8 (C/T) polymorphism with demographic and clinical characteristics among T2D and ND patients

From: Possible association between ABCC8 C49620T polymorphism and type 2 diabetes in a Nigerian population

	Type 2 Diabetes patients				Non-Diabetic patients
	CC genotype	CT genotype	TT genotype	p-value	CC genotype	CT genotype	TT genotype	p-value
Age (year)	58.67 ± 2.37	61.50 ± 2.59	55.05 ± 1.55	0.128	54.19 ± 3.22	47.46 ± 3.19	45.53 ± 2.89	0.111
WC (cm)	103.12 ± 2.89	104.00 ± 2.50	98.32 ± 2.37	0.342	88.12 ± 3.56	90.70 ± 6.86	89.94 ± 3.26	0.608
BMI (Kg/m²)	32.74 ± 3.09	29.31 ± 1.86	31.29 ± 1.83	0.764	26.82 ± 1.25	28.25 ± 1.76	28.46 ± 1.16	0.909
FBG (mg/dl)	203.99 ± 27.91	150.30 ± 13.73	153.19 ± 13.35	0.128	60.37 ± 3.18	56.77 ± 7.96	73.94 ± 7.26	0.146
TC (mg/dl)	259.88 ± 43.84	235.58 ± 10.16	318.20 ± 43.86	0.516	135.84 ± 10.65	203.46 ± 34.17	161.27 ± 5.29	0.010
TG (mg/dl)	224.97 ± 15.33	286.25 ± 19.69	237.82 ± 23.97	0.482	170.22 ± 14.96	169.68 ± 19.01	124.55 ± 7.51	0.010
LDL (mg/dl)	183.44 ± 46.36	141.22 ± 11.43	241.07 ± 44.22	0.445	75.39 ± 9.25	124.93 ± 36.14	64.64 ± 6.64	0.010
HDL (mg/dl)	31.12 ± 4.36	38.31 ± 7.02	33.46 ± 2.62	0.612	39.43 ± 2.81	44.63 ± 4.66	87.45 ± 9.11	<0.0001

Results showed a significantly (p < 0.05) lower TC, TG, LDLand higher HDL levels in non-diabetic patients with TT genotype. Results are expressed as mean ± S.E.M
S.E.M standard error of the mean, WC waist circumference, BMI body mass index, FBG Fasting blood glucose, TC total cholesterol, TG triglyceride, LDL low density lipoprotein cholesterol, HDL high density lipoprotein cholesterol

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