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Table 2 Association of ABCC8 C/T genotypes in participants based on risk models

From: Possible association between ABCC8 C49620T polymorphism and type 2 diabetes in a Nigerian population

Ā 

ABCC8 C/T genotypes

T2D (%)Ā patients

ND (%) patients

OR (95% CI)

p-value

Codominant model

CC

19 (12.8)

27 (18.2)

ā€“

Ā 

CT

10 (6.8)

13 (8.8)

ā€“

Ā 

(CC vs. CT vs. TT)

TT

44 (29.7)

35 (23.6)

0.56 (0.27-1.17)

1.04 (1.01-1.07)a

0.311

0.009a

Dominant model (TX)

CC

19 (12.8)

27 (18.2)

ā€“

Ā 

(CC vs. CTā€‰+ā€‰TTā€‰=ā€‰XT)

TTā€‰+ā€‰CT

54 (36.5)

48 (32.4)

1.60 (0.79-3.23)

2.13 (1.00-4.52)a

0.191

0.05a

Recessive model (CX)

CCā€‰+ā€‰CT

29 (19.6)

40 (27.0)

ā€“

Ā 

(CXā€‰=ā€‰CCā€‰+ā€‰CT vs. TT)

TT

44 (29.7)

35 (23.6)

1.73 (0.90-3.33)

2.39 (1.16-4.91)a

0.098

0.018a

Total (N)

73 (49.3)

75 (50.7)

Ā Ā 
  1. The results showed significant differences (p< 0.05) in genotype frequencies between the T2D and ND patients after adjusting for age for all models
  2. OR odd ratio OR, CI confidence interval, vs. versus, N number of participants
  3. aIndicates age adjustments of study participants