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Table 2 Demographics and clinical characteristics of DME and PDR cases and comparison to controls

From: Genome-wide association studies for diabetic macular edema and proliferative diabetic retinopathy

 

Controls

DME Cases

P

PDR Cases

P

Number

435

270

 

176

 

Age (yrs)

66.5 ± 12.6

65.9 ± 10.6

0.491

62.7 ± 10.6

<  0.001

Duration (yrs)

12.6 ± 7.1

19.2 ± 8.8

<  0.001

19.1 ± 8.9

<  0.001

Female

48.5%

43.0%

0.151

35.2%

0.003

Hypertension

76.8%

88.1%

<  0.001

87.5%

0.003

Nephropathy

12.2%

24.4%

<  0.001

29.5%

<  0.001

HbA1c (%)

7.5 ± 1.5

8.8 ± 1.8

<  0.001

8.9 ± 1.9

<  0.001

  1. For continuous variables, values are given as the mean ± standard deviation. For dichotomous variables, values are given as a %. HbA1c is a % of total haemoglobin. Duration = known duration of type 2 diabetes in years