Table 4 Presence or absence of the T allele of the rs6277 polymorphism of the DRD2 gene, according to sex and ethnicitya, and logistic regression analyses
From: Dopamine D2 receptor gene polymorphisms and externalizing behaviors in children and adolescents
Presence of the T allele (C/T and T/T) | Absence of the T allele (C/C) | p-value | χ2 | |||
Sex | ||||||
Female | 7 (35%) | 13 (65%) | 0.140 | 2.173 | ||
Male | 35 (53.8%) | 30 (46.2%) | ||||
Ethnicity | ||||||
African | 0 | 8 (100%) | b | b | ||
Bi-racial (African and Caucasian) | 8 (53.3%) | 7 (46.7%) | ||||
Caucasian | 34 (55.7%) | 27 (44.3%) | ||||
Asiana | 0 | 1 (100%) | ||||
CBCL 6/18 cluster of symptoms | Univariate analysis | Final multivariate stepwise analysis | ||||
Odds Ratio | 95% Confidence Interval | p-value | Odds Ratio | 95% Confidence Interval | p-value | |
Challenging and oppositional problems (without X with alteration) | ||||||
Sex | ||||||
Female/Male | 0.56 | 0.2–1.57 | 0.267 | – | – | – |
Ethnicity | ||||||
Caucasian/African | 1.46 | 0.33–6.56 | 0.619 | – | – | – |
Caucasian/Bi-racial | 2.83 | 0.82–9.76 | 0.099 | – | – | – |
Presence of the T allele of the rs6277 SNP of the DRD2 gene | ||||||
No/Yes | 2.78 | 1.15–6.71 | 0.023 | 2.78 | 1.15–6.71 | 0.023 |
Attention problems and hyperactivity (few X substantial alterations) | ||||||
Sex | ||||||
Female/Male | 0.66 | 0.23–1.92 | 0.444 | – | – | – |
Ethnicity | ||||||
Caucasian/African | 0.34 | 0.04–2.88 | 0.320 | – | – | – |
Caucasian/Bi-racial | 0.96 | 0.27–3.37 | 0.945 | – | – | – |
Presence of the T allele of the rs6277 SNP of the DRD2 gene | ||||||
No/Yes | 2.69 | 1.001–7.24 | 0.050 | 2.69 | 1.001–7.24 | 0.050 |