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Table 2 Genotypic distribution of the evaluated SNPs of the DRD2 gene, regarding demographic data, psychiatric diagnoses and use of psychopharmacological medications

From: Dopamine D2 receptor gene polymorphisms and externalizing behaviors in children and adolescents

 

rs6277

rs1799978a

C/C

C/T

T/T

A/A

A/G

Sex

 Female

13 (65%)

6 (30%)

1 (5%)

15 (75%)

5 (25%)

 Male

30 (46.2%)

31 (47.7%)

4 (6.2%)

51 (78.5%)

14 (21.5%)

Age

 8–10 years-old

6 (37.5%)

8 (50%)

2 (12.5%)

12 (75%)

4 (25%)

 11–15 years-old

24 (48%)

23 (46%)

3 (6%)

39 (78%)

11 (22%)

 More than 15 years-old

13 (68.4%)

6 (31.6%)

0

15 (78.9%)

4 (21.1%)

Intelligence quotient (IQ)

 Normal

33 (52.4%)

27 (42.9%)

3 (4.8%)

49 (77.8%)

14 (22.2%)

 Mild-Moderate intellectual disability

10 (45.5%)

10 (45.5%)

2 (9.1%)

17 (77.3%)

5 (22.7%)

Psychiatric condition

 Disruptive/aggressive

20 (47.6%)

19 (45.2%)

3 (7.1%)

34 (81%)

8 (19%)

 Hyperkinetic

16 (45.7%)

16 (45.7%)

3 (8.6%)

24 (68.6%)

11 (31.4%)

 Depressive

15 (51.7%)

12 (41.4%)

2 (6.9%)

24 (82.8%)

5 (17.2%)

 Autism

14 (70%)

5 (25%)

1 (5%)

16 (80%)

4 (20%)

 Phobic-anxious

10 (58.8%)

6 (35.3%)

1 (5.9%)

13 (76.5%)

4 (23.5%)

 Learning disturbances

5 (38.5%)

7 (53.8%)

1 (7.7%)

7 (53.8%)

6 (46.2%)

 Psychotic

2 (33.3%)

4 (66.7%)

0

5 (83.3%)

1 (16.7%)

Psychiatric medication

 Antipsychotics

43 (50.6%)

37 (43.5%)

5 (5.9%)

66 (77.6%)

19 (22.4%)

 Antidepressants

26 (56.5%)

17 (37%)

3 (6.5%)

38 (82.6%)

8 (17.4%)

 Psychostimulants

8 (34.8%)

12 (52.2%)

3 (13%)

18 (78.3%)

5 (21.7%)

 Clonidine

5 (45.5%)

6 (54.5%)

0

10 (90.9%)

1 (9.1%)

 Others

6 (40%)

7 (46.7%)

2 (13.3%)

11 (73.3%)

4 (26.7%)

  1. aThere were no individuals with the G/G genotype of the rs1799978 SNP of the DRD2 gene