Table 3 Odds ratios (OR) of the polymorphic rs5015480 HHEX genotypes for diabetesa in the population
Gene | Normal | Diabetes c | ||||
|---|---|---|---|---|---|---|
SNP | Subjects | Genotype | N (%) | N (%) | OR (95% CIb) | P-value |
HHEX | All | TT/TC | 3741 (96.9) | 364(95.8) | 1.00 (reference) | |
rs5015480 | (n = 4240) | CC | 119 (3.1) | 16(4.2) | 1.44(0.83–2.48) | 0.1915 |
Men | TT/TC | 2509 (96.8) | 285(96.6) | 1.00 (reference) | ||
CC | 83 (3.2) | 10(3.4) | 1.10(0.56–2.17) | 0.7736 | ||
Women | TT/TC | 1232 (97.2) | 79(92.9) | 1.00 (reference) | ||
CC | 36 (2.8) | 6(7.1) | 2.68(1.05–6.82) | 0.0389 | ||
All Healthy | 2235 (97.2) | 157(97.5) | 1.00 (reference) | |||
(n = 2461) | CC | 65 (2.8) | 4(2.5) | 0.82(0.29–2.31) | 0.7035 | |
Men | TT/TC | 1426 (96.7) | 121(99.2) | 1.00 (reference) | ||
CC | 48 (3.3) | 1(0.8) | 0.24(0.03–1.73) | 0.1545 | ||
Women | TT/TC | 809 (97.9) | 36(92.3) | 1.00 (reference) | ||
CC | 17 (2.1) | 3(7.7) | 4.46(1.15–17.3) | 0.0304 | ||