Table 2 Association between the rs5015480 single nucleotide polymorphism in the HHEX gene and fasting blood sugar levels based on a linear regression model
Genotypes | |||||
|---|---|---|---|---|---|
Phenotypes | TT | TC | CC | Effect | P-value |
Mean ± SD | Mean ± SD | Mean ± SD | (β) | ||
All subjects | (N = 2827) | (N = 1278) | (N = 135) | ||
Fasting blood sugar, mg/dL | 96.5 ± 21.7 | 97.8 ± 24.1 | 100.1 ± 28.1 | 1.572 | 0.0122 |
Systolic blood pressure, mmHg | 121.6 ± 14.0 | 122.6 ± 15.2 | 121.6 ± 14.9 | 0.721 | 0.0676 |
Diastolic blood pressure, mmHg | 78.3 ± 10.7 | 78.5 ± 11.1 | 75.6 ± 10.9 | −0.341 | 0.2541 |
Healthy subjects | (N = 1672) | (N = 720) | (N = 69) | ||
Fasting blood sugar, mg/dL | 94.0 ± 18.9 | 95.9 ± 21.8 | 94.8 ± 19.6 | 1.420 | 0.0545 |
Systolic blood pressure, mmHg | 119.2 ± 12.9 | 119.9 ± 13.8 | 119.3 ± 12.4 | 0.544 | 0.2585 |
Diastolic blood pressure, mmHg | 78.7 ± 10.8 | 79.0 ± 10.7 | 76.9 ± 10.0 | −0.044 | 0.9103 |