Fig. 1

Representative gel of the polymorphism pattern resulting from the restriction with XbaI of amplified samples for the estrogen receptor alpha. Samples with one band only indicate a wild profile (~ 1300 pb, eg., lane 12), whereas samples with three bands (~ 1300, ~ 900, and ~400pb, eg., lanes 2 and 5) and with two bands (~ 900 and ~400pb, eg., lanes 3 and 4) indicate the heterozygous and homozygous profiles for mutation, respectively. The arrows point to the migration of each of the expected fragments. P, molecular weight standard (100 pb step ladder – Promega)