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Table 3 Association of tanning dependent related single nucleotide polymorphisms and sun exposure variables

From: Influence of maternal and own genotype at tanning dependence-related SNPs on sun exposure in childhood

SNP (RA) Outcome Partly adjusted Fully adjusted
OR 95% CI p n OR 95% CI p n
 Childs SNPs
  rs60050811 (C) Usually used sun block or cream when out in the sun at age 8 years 1.34 1.11–1.62 .0025 4983 1.43 1.09–1.88 .0106 3438
 Mothers SNPs
  rs650662 (A) Factor of sun block or cream the child usually used at age 8 years a 0.89 0.82–0.96 .0020 4524 0.89 0.81–0.99 .0291 3459
  rs2073478 (T) Star system rating of child’s sun block or cream b 0.68 0.53–0.88 .0028 741 0.68 0.49–0.94 .0181 585
Analyses adjusted for sex and pigmentation
 Childs SNPs
  rs60050811 (C) Usually used sun block or cream when out in the sun at age 8 years 1.43 1.01–1.87 .0074 2549 1.29 0.90–1.86 .2651 1892
 Mothers SNPs
  rs650662 (A) Factor of sun block or cream the child usually used at age 8 yearsa 0.86 0.77–0.96 .0057 2385 0.88 0.77–1.01 .0627 1919
  rs2073478 (T) Star system rating of child’s sun block or cream b 0.58 0.40–0.82 .0021 416 0.58 0.38–0.89 .0131 338
  1. RA Risk allele (increases the risk of becoming TD, allele used based on findings from Cartmel et al. [13]); SNP Single nucleotide polymorphism
  2. The partly adjusted model adjusted for the mothers’ or child’s principal components (1–8 in the mother’s and child’s analysis respectively), and the age of the child (in months) when the questionnaire was completed. The fully adjusted model was adjusted for both the child and mother’s SNPs and principal components (1–2) and the age of the child (in months) when the questionnaire was completed
  3. a 0 = factor 0–7; 1 = factor 8–14; 2 = factor 15–20; 3 = factor 21–25; 4 = 25+
  4. b 0 = star rating 1–3, 1 = star rating 4