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Table 4 Association of Age and Allele/Genotype Frequencies of IL-10 and TGF-β Single Nucleotide Polymorphisms

From: Association of IL10 and TGFB single nucleotide polymorphisms with intervertebral disc degeneration in Iranian population: a case control study

Cytokine

Position

Alleles/ Genotypes

IVDD (N = 76)

Age ± SD (years)

P-Value

N (%)

TGF-β

Codon 10

C

76 (50)

39.51 ± 10.20

0.61

T

76 (50)

38.64 ± 11.00

CC

13 (17.1)

41.00 ± 8.05

0.77

CT

50 (65.8)

38.74 ± 11.21

TT

13 (17.1)

38.46 ± 11.03

TGF-β

Codon 25

C

12 (8)

35.08 ± 9.75

0.18

G

138 (92)

39.30 ± 10.64

CC

1 (1.3)

32.00

0.45

GC

10 (13.3)

35.70 ± 10.66

GG

64 (85.3)

39.58 ± 10.67

IL-10

-1082

A

93 (61.2)

39.40 ± 10.40

0.99

G

59 (38.8)

39.07 ± 10.95

AA

19 (25)

41.00 ± 10.76

0.026

GA

55 (72.4)

37.76 ± 10.14

GG

2 (2.6)

57.00 ± 2.82

IL-10

-819

C

88 (57.9)

39.50 ± 10.45

0.56

T

64 (42.1)

38.50 ± 10.81

CC

20 (26.3)

41.10 ± 9.86

0.58

CT

48 (63.2)

38.17 ± 10.94

TT

8 (10.5)

39.50 ± 11.07

IL-10

-592

A

73 (48)

38.75 ± 10.82

0.71

C

79 (52)

39.38 ± 10.42

AA

9 (11.8)

38.44 ± 10.93

0.86

CA

55 (72.4)

38.85 ± 10.98

CC

12 (15.8)

40.58 ± 9.31