Fig. 1From: A unique homozygous WRAP53 Arg298Trp mutation underlies dyskeratosis congenita in a Chinese Han familya Pedigree of a Chinese family affected with DC. The arrow indicates the proband with typical clinical symptoms. His heterozygous, consanguineous parents and sister had no clinical symptoms. b The affected proband with DC showed the typical signs of nail dysplasia and oral leukoplakia. c Bone marrow biopsy of the proband revealed severe hypocellularity (HE stain, × 400)Back to article page