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Table 4 P-values of comparisons of S100B SNPs on allele and genotype level in the pooled population

From: S100B polymorphisms are associated with age of onset of Parkinson’s disease

 

rs9722

rs2239574

rs881827

rs9984765

rs1051169

p-Valuea allele

*4.1 × 10 −6

0.448

0.043

0.007

0.028

p-Valuea genotype

*5.0 × 10 −5

0.233

0.131

0.018

0.049

p-Valueb allele

*0.003

0.912

0.132

0.016

0.038

p-Valueb genotype

0.015

0.731

0.289

0.034

0.079

ORc

2.9 (1.8–4.7)

1.1 (0.8–1.6)

1.4 (1.0–2.0)

1.6 (1.1–2.1)

1.4 (1.0–1.9)

  1. aEarly onset PD (≤50 years) compared to late onset PD (> 50 years). bEarly onset PD compared to controls. cOR (95% confidence interval) for early onset PD compared to controls. Significant (p < 0.05) results are shown in bold. With Bonferroni correction for multiple testing (analyses of 5 SNPs and 3 comparisons; controls versus all PD patients, controls versus early onset PD and early onset versus late onset PD) significant (p < 0.0033) results are shown by *. P-values were calculated from Chis-square test and ORs were calculated using logistic regression