| rs9722 | rs2239574 | rs881827 | rs9984765 | rs1051169 |
---|
p-Valuea allele |
*4.1 × 10
−6
| 0.448 |
0.043
|
0.007
|
0.028
|
p-Valuea genotype |
*5.0 × 10
−5
| 0.233 | 0.131 |
0.018
|
0.049
|
p-Valueb allele |
*0.003
| 0.912 | 0.132 |
0.016
|
0.038
|
p-Valueb genotype |
0.015
| 0.731 | 0.289 |
0.034
| 0.079 |
ORc |
2.9 (1.8–4.7)
| 1.1 (0.8–1.6) |
1.4 (1.0–2.0)
|
1.6 (1.1–2.1)
|
1.4 (1.0–1.9)
|
- aEarly onset PD (≤50 years) compared to late onset PD (> 50 years). bEarly onset PD compared to controls. cOR (95% confidence interval) for early onset PD compared to controls. Significant (p < 0.05) results are shown in bold. With Bonferroni correction for multiple testing (analyses of 5 SNPs and 3 comparisons; controls versus all PD patients, controls versus early onset PD and early onset versus late onset PD) significant (p < 0.0033) results are shown by *. P-values were calculated from Chis-square test and ORs were calculated using logistic regression