From: S100B polymorphisms are associated with age of onset of Parkinson’s disease
Discovery cohort | Validation cohort | All | |
---|---|---|---|
N | 896 | 573 | 1469 |
Controls | 465 | 378 | 843 |
Mean age | 74.1 | 67.5 | 70.8 |
Males (%) | 134 (28.8) | 187 (49.5) | 321 (38.1) |
PD Patients | 431 | 195 | 626 |
Mean age | 67.6 | 71.4 | 69.5 |
Males (%) | 258 (59.9) | 121 (62.1) | 379 (60.5) |
Mean age of onset | 59.3 | 63.6 | 61.5 |
Onset ≤50 y. of age (%) | 87 (20.2) | 25 (12.8) | 112 (17.9) |