The Alu-insertion progesterone receptor gene polymorphism is not associated with breast cancer: a meta-analysis

BMC Medical Genetics

Table 3 Summarized ORs with 95% CIs for the association between PGR polymorphism and breast cancer

Polymorphism	Genetic model	n	Statistical model	OR	95% CI	p_z	I²(%)	p_h	p_e
Alu insertion
	Allele contrast	10	Random	0.962	0.738–1.254	0.775	55.9	0.016	0.552
	Homozygous codominant	10	Random	0.948	0.325–2.763	0.922	58.7	0.013	0.132
	Heterozygous codominant	10	Random	1.019	0.535–1.939	0.955	87.3	< 0.001	0.776
	Dominant	10	Random	1.025	0.526–1.994	0.943	89.0	< 0.001	0.889
	Recessive	10	Random	0.948	0.440–2.042	0.892	48.5	0.042	0.389

Note: n, the number of studies; p_z, P value for association test; p_h, p value for heterogeneity test; p_e, p value for publication bias test

ISSN: 1471-2350