Skip to main content

Table 4 Relationship between rs1485175 and NIHL layered by CNE

From: Effect of GRM7 polymorphisms on the development of noise-induced hearing loss in Chinese Han workers: a nested case-control study

Environmental factor Genotype Case Control OR (95% CI) * p/pbon
   n % n %   
CNE, dB (A)
  < 97 TT 44 30.8 81 29.5 1 0.846/0.423
TC 74 51.7 138 50.2 1.023 (0.700, 1.496) 0.906/0.453
CC 25 17.5 56 20.4 0.895 (0.546, 1.469) 0.662/0.331
  > 97 TT 61 40.9 91 29.4 1 0.047/0.024
TC 65 43.6 138 44.7 0.784 (0.550, 1.118) 0.179/0.090
CC 23 15.4 80 25.9 0.550 (0.340, 0.891) 0.014/0.007
  1. The interaction between genes and the environment (CNE) analyzed by layering
  2. *Height, smoking, drinking, and hypertension are adjusted
  3. The statistically significant p values are adjusted by Bonferroni correction through 0.05/2 (2 groups layered by CNE) and it is statistically significant if pbon < 0.025