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Table 1 General characteristics according to genotypic groups of the patients

From: Quality of life scores differs between genotypic groups of patients with suspected hereditary hemochromatosis

  Group 1a, n = 29 Group 2b, n = 50 p value
Gender (male), % 44.8 84.0 0.001
Age (years), mean ± SD 45 ± 12 49 ± 12 0.14
Transferrin saturation (%), mean ± SD 86 ± 19 71 ± 12 < 0.001
Serum ferritin (ng/mL), mean ± SD 1669 ± 1209 1252 ± 750 < 0.001
Self-declared race/color, %
 White 82.7 82.0  
 Intermediate 17.3 12.0 0.35
 Others 0 6.0  
Level of education, %
 University 62.1 68.0 0.77
 Others 37.9 32.0
Consumption of alcoholic beverages, %
 Never 51.7 36.0  
 Occasionally 44.8 54.0 0.30
 Frequently 3.5 10.0  
  1. aGroup 1: patients with primary iron overload and homozygosity for the p.Cys282Tyr mutation
  2. bGroup 2: patients with primary iron overload and other genotypes: compound heterozygosity for the p.Cys282Tyr/p.His63Asp (n = 11), heterozygosity for the p.Cys282Tyr (n = 4), homozygosity (n = 12) or heterozygosity (n = 9) for the p.His63Asp, or absence of p.Cys282Tyr or and p.His63Asp (n = 14)