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Table 1 Filtering process of whole exome sequencing analysis in this study

From: Whole-exome sequencing identified a missense mutation in WFS1 causing low-frequency hearing loss: a case report

Patient (30–22)  
Total sequence reads 93,205,604
Matched Reads (percentage of reads) 91,298,272 (97.95%)
Total number of variants detected 187,202
Variants which are not common dbSNP138 (MAF > 1%) (A) 37,206
Variants which are not present in 32 control of healthy individuals 9487
Variants which are nonsynonymous or located in splice junction (B) 622
% B / A 1.67%
Located within splice site 31
Deletion/Insertion 33
Stop codon gained / Stop codon lost 5
Missense 553
SNPs after inspection of MAF < 0.05% & amino acid conservation 168
Located within splice site 7
Deletion/Insertion 3
Stop codon gained / Stop codon lost 5
Missense 153
Variant in 129 genes known to deafness genes 4
Sanger confirmation / Segregation 2
Causative mutation WFS1