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Fig. 1 | BMC Medical Genetics

Fig. 1

From: The gene–treatment interaction of paraoxonase-1 gene polymorphism and statin therapy on insulin secretion in Japanese patients with type 2 diabetes: Fukuoka diabetes registry

Fig. 1

Association of PON1 Q192R polymorphism with FPG (a), HbA1c (b), serum C-peptide (c), and HOMA2-%β (d) after stratified analysis by statin therapy. Data are expressed as adjusted mean (95% CI) referring to ANCOVA; P value refers to multiple regression analysis. FPG and HbA1c: adjusted for gender, age, BMI, smoking, alcohol, leisure-time physical activity, duration of diabetes, SU, glinide, thiazolidine, α-GI, biguanide, insulin. C-peptide and HOMA2-%β: adjusted for gender, age, BMI, smoking, alcohol, leisure-time physical activity, duration of diabetes, HbA1c, SU, glinide, thiazolidine, α-GI, biguanide, insulin. * P < 0.05 for trend in the group with statins

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