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Table 1 Summary of all currently known WISP3 gene mutations in PPD patients in China

From: Delayed-onset of progressive pseudorheumatoid dysplasia in a Chinese adult with a novel compound WISP3 mutation: a case report

No. Location Nucleotide change Amino acid change References
1 Exon 2 c.105dupT p.Gly36fs*10 [14]
2 Exon 2 c.208_209insA / [8]
3 Exon 2 c.136C > T p.Gln46* [2, 8, 13]
4 Exon 3 c.342 T > G p.Cys114Trp [8, 12,13,14,15]
5 Exon 3 c.342G > A p.Cys114Try [2]
6 Exon 4 c.624delA p.Lys208fs*24 [14]
7 Exon 4 c.624_625insA p.Cys209fs*229 [8]
8 Exon 4 c.667 T > G p.Cys223Gly [7, 8]
9 Exon 4 c.679dupA p.Cys227Leufs*21 [15]
10 Exon 4 c.716_722delAAATGAG p.Glu239fs*16 [12]
11 Exon 4 c.721 T > G p.Cys241Gly [15]
12 Exon 4 c.729_735delGAGAAAA p.Glu243fs*255 [8, 13]
13 Exon 4 c.756C > A p.Cys252* [7]
14 Exon 5 c.840delT p.Phe280Leufs*33 [11]
15 Exon 5 c.866_867insA p.Gln289fs*31 [8, 12]
16 Exon 5 c.866dupA p.Ser290Glufs*13 [13]
17 Exon 5 c.857C > G p.Ser286* [13]
18 Exon 5 c.1000 T > C p.Ser334Pro [11, 12]