Table 2 SNPs evaluated according to Hardy-Weinberg equilibrium. The allele information were showed as Reference allele/Risk allele. P < 0.05 in bold. SNPs. Single nucleotide polymorphism; MAF: Minor Alleles frequency; HWE: Hardy-Weinberg Equilibrium. MAF YRI Minor Alleles frequency of population African; MAF EUR Minor Alleles frequency of European according with 1000 genomes project
SNPs | Allele | MAF | HWE | Missing Genotypes (%) | MAF YRI | MAF EUR |
|---|---|---|---|---|---|---|
rs11749656 | C/A | 2.4 | 1.0000 | 3.1 | – | 5.0 |
rs1254167 | G/C | 8.7 | 1.0000 | 2.3 | 11.1 | 10.1 |
rs17026194 | G/A | 1.9 | 1.0002 | 1.2 | 5.5 | – |
rs17821714 | G/A | 3.7 | 1.0003 | 0.8 | – | 6.5 |
rs4245211 | A/G | 34.9 | 0.8885 | 5.8 | 40.7 | 26.7 |
rs6507639 | T/G | 7.1 | 1.0000 | 2.3 | 11.1 | 7,5 |
rs2910164 | G/C | 34.5 | 0.8899 | 1.9 | – | – |
rs6578493 | A/C | 19.9 | 0.8439 | 4.2 | 22.6 | 22.7 |
rs6825379 | A/G | 14.5 | 0.6189 | 3.1 | 30.5 | 5.0 |
rs664677 | T/C | 35.7 | 1.0000 | 4.2 | 19.4 | 44.4 |
rs10790373 | C/T | 27.8 | 0.7458 | 10 | 30.0 | 20.7 |
rs2651339 | A/C | 48.2 | 0.5273 | 4.6 | 44.4 | 48.4 |
rs566309 | C/T | 8.6 | 0.7043 | 1.5 | 11.1 | 9.6 |
rs2356508 | C/A | 8.7 | 1.0000 | 2.3 | 10.6 | 7.5 |
rs3744962 | T/C | 7.3 | 0.6285 | 2.3 | 0.9 | 8.5 |
rs17485896 | T/C | 22.7 | 0.4762 | 2.7 | 8.3 | 34.8 |
rs11856964 | A/C | 12.2 | 0.5525 | 1.9 | 14.3 | 13.1 |
rs1158257 | C/T | 46.9 | 0.7065 | 1.5 | 39.8 | 48.9 |
rs9943744 | C/T | 46.7 | 0.5285 | 2.3 | 28.2 | 42.9 |
rs7028661 | G/A | 31.0 | 0.3770 | 3.8 | 15.7 | 35.3 |
rs258107 | C/T | 27.9 | 0.4344 | 3.5 | 17.1 | 30.3 |
rs9993140 | G/A | 3.9 | 0.3222 | 2.3 | 15.2 | 1.5 |
rs31872 | T/C | 22.7 | 0.1938 | 8.5 | 8.8 | 33.8 |
rs11720059 | G/A | 6.0 | 0.2120 | 3.5 | – | 9.0 |
rs949908 | T/A | 47.6 | 0.1593 | 5.8 | 45.3 | 45.4 |
rs965513 | G/A | 29.1 | 0.2244 | 1.5 | 13.4 | 35.5 |
rs4075022 | T/C | 28.2 | 0.0827 | 5.8 | 6.0 | 43.4 |
rs12137541 | G/A | 22.4 | 0.0701 | 2.3 | 16.6 | 27.7 |
rs1801516 | G/A | 12.3 | 0.0869 | 1.2 | – | 18.1 |
rs1499008 | G/A | 37.2 | 0.1066 | 2.7 | 22.2 | 47.4 |
rs1461855 | T/A | 20.2 | 0.0799 | 1.9 | 45.8 | 8.0 |
rs2839582 | T/C | 40.7 | 0.0671 | 3.1 | 47.6 | 29.2 |
rs4075570 | G/A | 49.2 | 0.1263 | 5.0 | 39.3 | 38.8 |
rs7037324 | G/A | 26.5 | 0.0504 | 3.5 | 7.4 | 39.3 |
rs6983267 | G/T | 31.0 | 0.0236 | 6.9 | 2.7 | 48.4 |
rs4698951 | T/C | 26.8 | 0.0103 | 1.2 | 37.9 | 6.0 |
rs17072086 | T/C | 15.9 | 0.0038 | 1.9 | 0.4 | 22.7 |
rs2284734 | G/A | 46.3 | 0.0027 | 1.2 | 20.8 | 33.8 |
rs2997312 | G/A | 28.1 | 0.0079 | 2.3 | 43.9 | 12.6 |
rs10912963 | G/C | 40.9 | 0.0059 | 4.6 | 17.5 | 44.9 |
rs12206214 | G/A | 28.8 | 0.0056 | 3.1 | 17.5 | 42.9 |
rs13447450 | C/T | 17.4 | 0.0007 | 1.5 | 0.9 | 37.8 |
rs162270 | G/T | 15.1 | 0.0002 | 2.7 | – | – |
rs9937860 | T/G | 15.1 | 0.0002 | 3.5 | 16.6 | 12.1 |
rs944289 | C/T | 38.1 | 0.00004 | 1.2 | 12.9 | 39.3 |