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Table 1 Baseline characteristics of the cohort
| Variables | Cases (n = 257) | Controls (n = 537) | P value |
|---|---|---|---|
| Female sex, No. (%) | 35 (14) | 131 (25) | 0.001 |
| Median Age at index infarction, y (IQR) | 60 (53–68) | 61 (52–66) | 0.100 |
| Cardiovascular risk profile | |||
| Body mass index (kg/m2), (IQR) | 27.2 (25–29) | 26.7 (24–29) | 0.400 |
| Smoking (pack year), (IQR) | 25 (5–41) | 25 (6–42) | 0.200 |
| Smoking, No. (%) | |||
| Never | 38 (16) | 108 (20) | 0.300 |
| Past | 69 (28) | 133 (25) | |
| Current | 136 (56) | 290 (55) | |
| Alcohol per week, (unit*, IQR) | 6 (1–15) | 3 (0–9) | <0.001 |
| Alcohol units per week (categorized), No. (%) | |||
| Non-drinkers | 46 (19) | 143 (27) | <0.001 |
| Normal (1–7) | 90 (38) | 242 (46) | |
| Moderate High (8–14) | 41 (17) | 70 (13) | |
| High (>15) | 60 (26) | 73 (14) | |
| Diabetes, No. (%) | 30 (12) | 47 (9) | 0.200 |
| Hypertension, No. (%) | 102 (41) | 184 (35) | 0.070 |
| COPD, No. (%) | 12 (5) | 30 (6) | 0.700 |
| Hypercholesterolemia, No. (%) | 97 (39) | 165 (31) | 0.023 |
| Stroke, No. (%) | 18 (7) | 26 (5) | 0.200 |
| Atrial fibrillation, No. (%) | 16 (7) | 10 (2) | 0.006 |
| Depression, No. (%) | 28 (11) | 65 (12) | 0.700 |
| Epilepsy, No. (%) | 4 (2) | 5 (1) | 0.500 |
| Family History, No. (%) | |||
| Sudden death | 94 (40%) | 128 (25%) | <0.001 |
| Myocardial infarction | 90 (40%) | 195 (38%) | 0.600 |
| Stroke | 36 (16%) | 75 (15%) | 0.600 |
| Medication before MI¶, No. (%) | |||
| β-blockers | 20 (8) | 43 (8) | 0.900 |
| Statins | 55 (22) | 65 (12) | <0.001 |
| ACE/ARB blockers | 50 (21) | 90 (17) | 0.200 |
| Aspirin | 28 (12) | 40 (8) | 0.060 |
