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Table 2 Genotypic and allelic frequencies of G-6-PD deficiency in Burkina Faso

From: Prevalence, genetic variants and clinical implications of G-6-PD deficiency in Burkina Faso: a systematic review

Genotypes n/Study N %
a,b,c Total Total
Male
 B 99 + 41 + 54 194 55.27
 A 49 + 31 + 24 104 29.63
 A- 27 + 12 + 14 53 15.10
 Total 175 + 84 + 92 351 100.00
Female
 BB 55 + 40 + 38 133 34.28
 BA 53 + 27 + 22 102 26.29
 AA 18 + 10 + 5 33 8.51
 BA- 35 + 26 + 12 73 18.81
 AA- 15 + 6 + 9 30 7.73
 A-A- 6 + 7 + 4 17 4.38
 Total 182 + 116 + 90 388 100.00
  1. a = Carter et al., [27]; b = Ouattara et al., [14]; c = Ouattara et al., [28]. The data in this table come from these three references (a, b and c) with information allowing the calculation of the different haplotypes. The populations a, b and c from Ouagadougou with symptomatic or asymptomatic malaria as shown in Table 1, were conform to Hardy-Weinberg Equilibrium
  2. \( \mathbf{f}\ \left(\mathbf{B}\ \mathbf{haplotype}\right)=\frac{194+\left(133\ast 2\right)+102+73}{351+\left(388\ast 2\right)}=\mathbf{0.563} \)
  3. \( \mathbf{f}\ \left(\mathbf{A}\ \mathbf{haplotype}\right)=\frac{104+102+\left(33\ast 2\right)+30}{351+\left(388\ast 2\right)}=\mathbf{0.268} \)
  4. \( \mathbf{f}\ \left(\mathbf{A}\hbox{-} \mathbf{haplotype}\right)=\frac{53+73+30+\left(17\ast 2\right)}{351+\left(388\ast 2\right)}=\mathbf{0.169} \)