|
Genotypes
|
n/Study
|
N
|
%
|
|---|
|
a,b,c
|
Total
|
Total
|
|---|
|
Male
|
|
B
|
99 + 41 + 54
|
194
|
55.27
|
|
A
|
49 + 31 + 24
|
104
|
29.63
|
|
A-
|
27 + 12 + 14
|
53
|
15.10
|
|
Total
|
175 + 84 + 92
|
351
|
100.00
|
|
Female
|
|
BB
|
55 + 40 + 38
|
133
|
34.28
|
|
BA
|
53 + 27 + 22
|
102
|
26.29
|
|
AA
|
18 + 10 + 5
|
33
|
8.51
|
|
BA-
|
35 + 26 + 12
|
73
|
18.81
|
|
AA-
|
15 + 6 + 9
|
30
|
7.73
|
|
A-A-
|
6 + 7 + 4
|
17
|
4.38
|
|
Total
|
182 + 116 + 90
|
388
|
100.00
|
-
a = Carter et al., [27]; b = Ouattara et al., [14]; c = Ouattara et al., [28]. The data in this table come from these three references (a, b and c) with information allowing the calculation of the different haplotypes. The populations a, b and c from Ouagadougou with symptomatic or asymptomatic malaria as shown in Table 1, were conform to Hardy-Weinberg Equilibrium
-
\( \mathbf{f}\ \left(\mathbf{B}\ \mathbf{haplotype}\right)=\frac{194+\left(133\ast 2\right)+102+73}{351+\left(388\ast 2\right)}=\mathbf{0.563} \)
-
\( \mathbf{f}\ \left(\mathbf{A}\ \mathbf{haplotype}\right)=\frac{104+102+\left(33\ast 2\right)+30}{351+\left(388\ast 2\right)}=\mathbf{0.268} \)
-
\( \mathbf{f}\ \left(\mathbf{A}\hbox{-} \mathbf{haplotype}\right)=\frac{53+73+30+\left(17\ast 2\right)}{351+\left(388\ast 2\right)}=\mathbf{0.169} \)
