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Table 2 Genotypic and allelic frequencies of G-6-PD deficiency in Burkina Faso

From: Prevalence, genetic variants and clinical implications of G-6-PD deficiency in Burkina Faso: a systematic review

Genotypes

n/Study

N

%

a,b,c

Total

Total

Male

 B

99 + 41 + 54

194

55.27

 A

49 + 31 + 24

104

29.63

 A-

27 + 12 + 14

53

15.10

 Total

175 + 84 + 92

351

100.00

Female

 BB

55 + 40 + 38

133

34.28

 BA

53 + 27 + 22

102

26.29

 AA

18 + 10 + 5

33

8.51

 BA-

35 + 26 + 12

73

18.81

 AA-

15 + 6 + 9

30

7.73

 A-A-

6 + 7 + 4

17

4.38

 Total

182 + 116 + 90

388

100.00

  1. a = Carter et al., [27]; b = Ouattara et al., [14]; c = Ouattara et al., [28]. The data in this table come from these three references (a, b and c) with information allowing the calculation of the different haplotypes. The populations a, b and c from Ouagadougou with symptomatic or asymptomatic malaria as shown in Table 1, were conform to Hardy-Weinberg Equilibrium
  2. \( \mathbf{f}\ \left(\mathbf{B}\ \mathbf{haplotype}\right)=\frac{194+\left(133\ast 2\right)+102+73}{351+\left(388\ast 2\right)}=\mathbf{0.563} \)
  3. \( \mathbf{f}\ \left(\mathbf{A}\ \mathbf{haplotype}\right)=\frac{104+102+\left(33\ast 2\right)+30}{351+\left(388\ast 2\right)}=\mathbf{0.268} \)
  4. \( \mathbf{f}\ \left(\mathbf{A}\hbox{-} \mathbf{haplotype}\right)=\frac{53+73+30+\left(17\ast 2\right)}{351+\left(388\ast 2\right)}=\mathbf{0.169} \)