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Table 2 Case–control genotype data analysis

From: An intronic single-nucleotide polymorphism (rs13217795) in FOXO3 is associated with asthma and allergic rhinitis: a case–case–control study

 

Controla

Asthma

Allergic rhinitis

n b

n b

ORc (95% CI)

n b

ORc (95% CI)

General

 CC

19 (20%)

14 (11%)

1

15 (14%)

1

 CT

54 (57%)

61 (49%)

1.46 (0.64 to 3.34)

48 (44%)

1.05 (0.46 to 2.40)

 TT

21 (22%)

49 (40%)

3.42 (1.37 to 8.57)

47 (43%)

2.35 (0.96 to 5.73)

P value

  

0.01

 

0.046

Recessive

 CC + CT

73 (78%)

75 (60%)

1

63 (57%)

1

 TT

21 (22%)

49 (40%)

2.54 (1.33 to 4.85)

47 (43%)

2.26 (1.19 to 4.30)

P value

  

0.005

 

0.01

Dominant

 CC

19 (20%)

14 (11%)

1

15 (14%)

1

 CT + TT

75 (80%)

110 (89%)

1.96 (0.89 to 4.33)

95 (86%)

1.43 (0.65 to 3.12)

P value

  

0.1

 

0.4

  1. a The control group is the reference group for all comparisons
  2. b Absolute (relative) counts of participants
  3. c Odds ratios with 95% confidence intervals, adjusted for age and gender