BMC Medical Genetics

Table 1 Descriptive analysis results. Characteristics of cases and controls

From: The RS4939827 polymorphism in the SMAD7 GENE and its association with Mediterranean diet in colorectal carcinogenesis

		CONTROLS		CASES		p-values
		N	%	N	%
		2409		1087		–
Age	(Mean/SD)	63.13	11.5	66.64	10.4	–
Sex	Men	1300	54	708	65.1	<0.0001
Sex	Women	1109	46	379	34.9	<0.0001
First Degree Family History	No	2081	90.6	855	82.1	<0.0001
First Degree Family History	Yes	216	9.4	186	17.9	<0.0001
Cultural level	Less than primary school	409	17	288	26.5	<0.0001
	Primary school	803	33.3	458	42.1
	Secundary school	698	29	221	20.3
	University	499	20.7	120	11
BMI	Normal weight	759	31.5	259	23.8	<0.0001
	Less than normal weight	23	1	13	1.2
	Overweight	873	36.2	399	36.7
	Obesity	754	31.3	416	38.3
Total energy (Kcal/Day)	Low	795	33	296	27.2	<0.0001
	Medium	794	33	320	29.4
	High	820	34	471	43.3
METS	Sedentarism	855	35.5	468	43.1	<0.0001
	Low physical activity	385	16	134	12.3
	Moderate physical activity	313	13	109	10
	High physical activity	856	35.5	376	34.6

N Number, BMI Body Mass Index, METS Metabolic Equivalent of Task. The cut point for category of total energy are <1586.3 Kcal/day, ≥ 1586.3 Kcal/day & < 2046.4 Kcal/day and ≤2046.4 for low, medium and high level respectively.For the physical activity, the cut points are 0 when the there is no physical activity, < 8 METS*hours/week for low physical activity, ≥ 8 and < 16 METS*hours/week for moderated physical activity and >16 METS*hours/week for high physical activity (according to American College of Sport Medicine)

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