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Table 1 Phenotypic spectrum of WAGR syndrome with 10 Mb or larger deletions

From: Sustained endocrine profiles of a girl with WAGR syndrome

No Case ID Age Sex Reference (Author, Year) Cytoband Size (Mb) Genome
Assembly
Start point End point Height Body
weight
Neurological Signsa
1 F24a 16 F Xu S, 2008 [4] 11p12p15.1 23.0 GRCh 35 (hg17) 20,040,419 43,071,919 NA NA ID, OCD
2 F8a 11 F Xu S, 2008 [4] 11p14p12.3 19.1 GRCh 35 (hg17) 25,086,501 44,212,278 NA NA ID, OCD, ASD
3 NIH10 6 M Xu S, 2008 [4] 11p11.2p14.1 18.2 GRCh 35 (hg17) 27,656,700 45,858,752 NA NA DD
4 F17a 36 F Xu S, 2008 [4] 11p14p12.3 15.6 GRCh 35 (hg17) 25,086,501 40,651,423 NA NA ID, ASD, ADHD,
OCD, Anxiety
5 NIH3 4 M Xu S, 2008 [4] 11p14p12.3 15.3 GRCh 35 (hg17) 24,202,909 39,529,029 NA NA DD
6 F10a 7 F Xu S, 2008 [4] 11p11.2p13 14.9 GRCh 35 (hg17) 31,284,414 46,194,871 NA NA ID, DD, OCD,
Anxiety
7 F20a 15 M Xu S, 2008 [4] 11p14p12.3 14.6 GRCh 35 (hg17) 25,844,571 40,482,022 NA NA ID, DD, ASD,
ADHD, OCD,
Anxiety
8 YS 013 5 F [This study] 11p14.3p12 14.4 GRCh37 (hg19) 24,792,569 39,222,929 91.3 cm
(−3.5 SD)
12.45 kg
(−2.2 SD)
DD, ASD,
Hyperphagia
9 NIH9 7 F Xu S, 2008 [4] 11p13p15.1 14.4 GRCh 35 (hg17 20,759,560 35,124,532 NA NA ID, ASD
10 F7a 13 F Xu S, 2008 [4] 11p14p12.3 14.3 GRCh 35 (hg17 24,542,321 38,824,714 NA NA ASD, DD, ADHD
11 NIH6 17 M Xu S, 2008 [4] 11p14p12.2 14.2 GRCh 35 (hg17 26,005,134 40,174,102 NA NA ID, ASD, ADHD,
Anxiety
12 NIH2 19 M Xu S, 2008 [4] 11p13p15.1 13.5 GRCh 35 (hg17 20,135,621 33,614,001 NA NA ID, ASD
13 F3a 26 F Xu S, 2008 [4] 11p12p13 12.9 GRCh 35 (hg17 31,284,414 44,212,278 NA NA ID, DD, Seizure,
Depression
14 F21a 12 F Xu S, 2008 [4] 11p14p12.3 12.5 GRCh 35 (hg17) 25,336,593 37,873,278 NA NA ADHD, OCD,
Anxiety
15 F14a 12 F Xu S, 2008 [4] 11p14p12.1 12.2 GRCh 35 (hg17) 28,001,853 40,239,548 NA NA ID, ASD, OCD,
Anxiety, ADHD
16 F1a 11 M Xu S, 2008 [4] 11p13p14.3 11.4 GRCh 35 (hg17) 24,848,855 36,266,146 NA NA ID, ASD, Anxiety,
OCD
17 NIH11 4 M Xu S, 2008 [4] 11p14p12.2 10.7 GRCh 35 (hg17) 26,690,778 37,341,623 NA NA ID, ASD
18 F23a 16 M Xu S, 2008 [4] 11p14p12.1 10.6 GRCh 35 (hg17) 27,675,634 38,235,380 NA NA ID, ASD, DD, OCD
19 Patient 2 2 F Yamamoto T,
2013 [13]
11p13p12 10.5 GRCh 35 (hg17) 32,990,627 43,492,580 75.6 cm
(−3.5SD)
11.9 kg
(+0.8SD)
DD
20 NIH1 26 M Xu S, 2008 [4] 11p14p12.1 10.2 GRCh 35 (hg17) 27,692,635 37,916,281 NA NA ID, ASD
21 F19a 5 M Xu S, 2008 [4] 11p14p12.2 10.1 GRCh 35 (hg17) 26,699,475 36,757,882 NA NA ID, DD, ASD
  1. a Abbreviations: ID intellectual disability, OCD obsessive compulsive disorder, ASD, autism spectrum disorder, DD, developmental delay, ADHD, attention deficit hyperactive disorder