Gene expression profiling of idiopathic interstitial pneumonias (IIPs): identification of potential diagnostic markers and therapeutic targets

Table 1 Clinical characteristics of idiopathic interstitial pneumonia cases

Variables	Microarray cohort	IHC cohort
	(n = 12)	(n = 10)
Age (years)	66.2 ± 2.1	63.1 ± 1.9
Gender (male/female)*	9/3	7/3
Smoking history (Smoker/non-smoker) *	9/3	7/3
Pack-years*	23.8 ± 6.9	26.4 ± 7.8
Disease category (IPF/ NSIP)	7/5	5/5
Pulmonary function test
VC (% predicted)	86.0 ± 6.2	88.9 ± 6.6
DLco (% predicted)	57.2 ± 5.3	54.1 ± 5.5

Values are expressed as mean ± SEM or as a number
*P < 0.05 (Mann-Whitney U or χ² test between two groups)
IHC immunohistochemical analysis, IPF idiopathic pulmonary fibrosis, NSIP nonspecific interstitial pneumonia, VC vital capacity, DL _CO single-breath carbon monoxide diffusing capacity

ISSN: 1471-2350