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Table 4 In silico protein prediction effect of DAND5 p.Arg152His alteration

From: Functional study of DAND5 variant in patients with Congenital Heart Disease and laterality defects

  Score Prediction effect
PolyPhen-2 0,120 Benign
Mutation Taster Polymorphism Might affect protein features
PROVEAN -2,84 (cutoff = −2,5) Deleterious
I-Mutant 3.0 −1,28 Kcal/mol Reduced stability of the protein and related to disease