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Table 3 Haplotype analysis of the FSHR three SNPs rs6165, rs6166 and rs1394205

From: The susceptibility of FSHB -211G > T and FSHR G-29A, 919A > G, 2039A > G polymorphisms to men infertility: an association study and meta-analysis

Haplotype

Control (n = 340) Frequency

Case (n = 255)

Sperm concentration(<5 ×106/ml) (n = 166)

Sperm concentration(5–15 ×106/ml) (n = 89)

Frequency

P

OR(95%CI)

Frequency

P

OR(95%CI)

Frequency

P

OR(95%CI)

FSHR rs1394205/rs6165/rs6166

 AAA

0.376

0.382

0.794

1.03 (0.81–1.31)

0.366

0.652

0.94 (0.72–1.23)

0.427

0.163

1.27 (0.91–1.79)

 AGG

0.121

0.133

0.539

1.11 (0.79–1.57)

0.146

0.308

1.22 (0.83–1.79)

0.100

0.467

0.82 (0.48–1.41)

 GAA

0.309

0.269

0.133

0.82 (0.64–1.06)

0.287

0.408

0.89 (0.66–1.18)

0.219

0.022

0.63 (0.43–0.94)

 GGG

0.161

0.181

0.351

1.16 (0.85–1.57)

0.170

0.764

1.06 (0.74–1.50)

0.209

0.111

1.40 (0.92–2.13)

FSHR rs6165/rs6166

 AA

0.685

0.669

0.430

0.92 (0.74–1.14)

0.653

0.256

0.85 (0.64–1.13)

0.678

0.729

0.96 (0.76–1.22)

 GG

0.282

0.296

0.579

1.06 (0.86–1.32)

0.317

0.256

1.18 (0.89–1.57)

0.285

0.946

1.01 (0.79–1.29)

  1. Bold numbers mean statistically significant results