The susceptibility of FSHB -211G > T and FSHR G-29A, 919A > G, 2039A > G polymorphisms to men infertility: an association study and meta-analysis

Table 1 General characteristics of the study group

Clinical parameters	Fertile controls (n = 340)		Infertile cases (n = 255)		Azoospermic or severe oligozoospermia (n = 166)		Oligospermia (n = 89)
Clinical parameters	number	Mean ± SD	number	Mean ± SD	number	Mean ± SD	number	Mean ± SD
Age (years)	340	28.37 ± 4.23	255	28.49 ± 4.51	166	28.45 ± 4.34	89	28.56 ± 4.83
T (9.4-37 nmol/L)	32	12.43 ± 4.83	71	12.34 ± 4.74	52	13.18 ± 4.60	19	13.78 ± 5.20
FSH (1–5.5 IU/L)	32	4.72 ± 2.51	70	15.73 ± 16.15	52	19.28 ± 17.32	18	5.46 ± 2.80
LH (1–6.3 IU/L)	32	3.37 ± 1.46	70	6.46 ± 4.98	52	7.42 ± 5.41	18	3.69 ± 1.49
E₂ (58.6–194.2 pmol/L)	24	103.87 ± 77.35	42	112.00 ± 68.07	29	107.10 ± 71.75	13	122.92 ± 60.25
pH (7.2–7.4)	177	7.38 ± 0.06	89	7.37 ± 0.07	40	7.38 ± 0.53	49	7.36 ± 0.78
Semen volume (1.5-6 ml)	177	3.51 ± 1.39	89	3.78 ± 1.77	40	3.52 ± 1.27	49	3.98 ± 2.09
Sperm concentration (≥15 × 10⁶/ml)	340	72.77 ± 45.21	255	3.15 ± 4.52	166	0.27 ± 0.88	89	8.53 ± 3.55
Sperm motility (PR ≥ 32%)	340	42.02 ± 9.04	255	11.76 ± 17.76	166	1.32 ± 4.92	89	31.24 ± 16.61

SD standard deviation. Bold numbers was considered to be statistically significant compared with the controls

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