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Table 2 Interaction analyses of the HIF3A rs3826795 polymorphism and obesity on plasma ALT

From: Interaction between obesity and the Hypoxia Inducible Factor 3 Alpha Subunit rs3826795 polymorphism in relation with plasma alanine aminotransferase

  Mean ± SD of logALT (IU/L)    
  AA (n = 535) AG (n = 985) GG (n = 468) β’ P P inter
Total 1.11 ± 0.27 1.12 ± 0.27 1.14 ± 0.28 0.020 0.340  
Non-obese 1.04 ± 0.25 1.06 ± 0.23 1.05 ± 0.23 −0.009 0.741 0.042
Obese 1.24 ± 0.26 1.25 ± 0.30 1.30 ± 0.29 0.075 0.037
  1. β’ stands for the standardized coefficient of G allele number in the model
  2. P inter stands for the P value of the interaction term in the linear regression model, including logALT as the dependent variable, and SNP, obesity group, SNP × obesity group, age, age2 and gender as independent variables
  3. HIF3A: Hypoxia Inducible Factor 3 Alpha Subunit; ALT alanine aminotransferase