Table 1 Somatic mutational profiling of APC gene exon 14 using PCR-RFLP
From: Novel APC gene mutations associated with protein alteration in diffuse type gastric cancer
Codon | Enzymes | Size of normal alleles (bp) | Mutation | Amino acids | Size of mutant alleles | Sample Frequency |
|---|---|---|---|---|---|---|
622b | MspI | 189,163 | TAC > TAA | Y > a | 352 | 10% |
625b | MaeI | 266, 86 | CAG > TAG | Q > a | 135, 131, 86 | 5% |