Fig. 3

Circos plot of representative APC mutation in gastric tumor sample and their association with cancer stages, cell cycle, and APC protein expression. The frequency of occurrence of different factors such as mutations, APC protein expression pattern, ploidy level and tumor stages is depicted in the outer ring. The inner ring of circos plot depicts the association between the mutations, APC protein expression pattern, ploidy level and tumor stage involved in gastric cancer. Each factor has been assigned a color. The arc originates from mutations and APC protein expression status and terminates at tumor staging and ploidy level to compare the association between the origin and terminating factors. The area of each colored ribbon depicts the frequency of the samples related with the particular mutations and APC protein expression