Fig. 2From: KCNJ11, ABCC8 and TCF7L2 polymorphisms and the response to sulfonylurea treatment in patients with type 2 diabetes: a bioinformatics assessmentA schematic representation of 10 KCNJ11 missense SNPs in the protein product. Each Kir6.2 subunit (i.e., KCNJ11 protein product) contains two transmembrane domains, M1 and M2. Between M1 and M2, there is a pore-forming loop that creates the core of the K+ channelBack to article page