Table 1 The comparison of urine excretion of metabolites related to primary hyperoxaluria and ketosis in patient and control urine samples with/without ketosis. Values are expressed in mmol/mol creatinine as means ± standard deviation (BAIB - β-aminoisobutyric acid, HBA - 3-hydroxybutyrate; HIBA - 3-hydroxyisobutyric acid; HPA - 3-hydroxypropionic acid; EHPA - 2-ethyl-3-hydroxypropionic acids)
Metabolite | Control samples with ketosis (n = 11) | Control samples without ketosis (n = 11) | Patient with ketosis | Patient without ketosis |
|---|---|---|---|---|
Glycerate | 1.54 ± 1.34 | 0.97 ± 0.67 | 2796 | 1113 |
Oxalate | 29.1 ± 17.1 | 37.1 ± 19.2 | 349 | 167 |
Glycolate | 92.1 ± 62.3 | 51.3 ± 26.7 | 69 | 106 |
HBA | 1890 ± 2481 | 5.1 ± 6.6 | 605 | 2.1 |
HIBA | 20.0 ± 16.7 | 10.6 ± 5.5 | 80 | 29.5 |
HPA | 28.9 ± 35.2 | 3.9 ± 2.4 | 593 | 132 |
EHPA | 13.9 ± 13.6 | 4.0 ± 1.5 | 38.2 | 6.1 |
BAIB | 54.2 ± 33.5 | 15.7 ± 8.1 | 137 | 27 |