Table 6 Genotype and allele association analysis of three tagSNPs

rs2282175

CC

339 (83.7)

415 (88.9)

5.1

0.08

1

CT

62 (15.3)

48 (10.3)

1.63 (1.06–2.38)

0.026

0.054

TT

4 (1.0)

4 (0.9)

1.21 (0.30–5.00)

0.776

0.817

CT/TT

1.56 (1.05–2.27)

0.027

0.054

C

740 (91.4)

878 (94.0)

4.5

0.033

1

T

70 (8.6)

56 (6.0)

1.49 (1.03–2.12)

0.033

0.06

rs12493175

CC

311 (75.7)

308 (66.2)

12.7

0.002

1

CT

85 (20.7)

145 (31.2)

0.58 (0.42–0.79)

0.001

0.005

TT

15 (3.6)

12 (2.6)

1.23 (0.57–2.70)

0.589

0.736

CT/TT

0.62 (0.46–0.84)

0.002

0.007

C

707 (86.0)

761 (81.8)

5.6

0.017

1

T

115 (14.0)

169 (18.2)

0.73 (0.56–0.95)

0.017

0.0486

rs13062955

CC

305 (75.9)

281 (66.0)

15.1

0.001

1

AC

82 (20.4)

136 (31.9)

0.55 (0.40–0.76)

2.95 × 10⁻⁴

0.002

AA

15 (3.7)

9 (2.1)

1.53 (0.66–3.57)

0.318

0.424

AC/AA

0.61 (0.45–0.84)

0.002

0.007

C

692 (86.1)

698 (81.9)

5.2

0.021

1

A

112 (13.9)

154 (18.1)

0.73 (0.56–0.96)

0.021

0.053