Fig. 1From: A novel mutation in homeobox DNA binding domain of HOXC13 gene underlies pure hair and nail ectodermal dysplasia (ECTD9) in a Pakistani familyPedigree and haplotype of the family (a). Sequence analysis of the HOXC13 gene showing homozygous affected member (b), heterozygous carrier (c) and homozygous unaffected member (d). Clustal alignment of HOXC13 shows complete evolutionary conservation of the Asn310 residue (shaded) in all species with known ortholog (e)Back to article page