Family members | Age of onset (years) | Nucleotide change | At the beginning of this study (2014) | Follow-up (2016) | Tinnitus (No or Yes) | Exposure to noise (No or Yes) | Ototoxic drugs expose (No or Yes) | Vertigo (No or Yes) | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PTA | DPOAE | PTA | DPOAE | |||||||||||
Right | Left | Right | Left | Right | Left | Right | Left | |||||||
IV:8 | 25 | c.887G > A | 90 | 77.5 | Absent at all frequencies | Absent at all frequencies | 95 | 90 | Absent at all frequencies | Absent at all frequencies | Yes | No | No | No |
V:1 | 15 | c.887G > A | 116.25 | 97.5 | Absent at all frequencies | Absent at all frequencies | 110 | 93.75 | Absent at all frequencies | Absent at all frequencies | Yes | No | No | No |
V:2 | - | wildtype | 15 | 12.5 | Not examined | Not examined | 20 | 15 | Not examined | Not examined | No | No | No | No |
V:3 | - | wildtype | 13.75 | 28.75 | Not examined | Not examined | 15 | 33.75 | Normal | Normal at 1 and 2 KHz and absent at other frequencies | No | Yes | No | No |
V:5 | 30 | c.887G > A | 58.75 | 55 | Absent at all frequencies | Absent at all frequencies | 50 | 48.75 | Absent at all frequencies | Absent at all frequencies | Yes | No | No | No |
V:7 | - | wildtype | 20 | 17.5 | Not examined | Not examined | 15 | 18.75 | Normal | Normal | No | No | No | No |
VI:1 | 18 | c.887G > A | 77.5 | 61.25 | Absent at all frequencies | Absent at all frequencies | 88.75 | 103.8 | Absent at all frequencies | Absent at all frequencies | Yes | No | No | No |
VI:2 | 21 | c.887G > A | 40 | 42.5 | Not examined | Not examined | 42.5 | 45 | Not examined | Not examined | Yes | No | No | No |