|
AML (p < 0.01 and q < 0.10)
|
|
NEFH
|
22
|
In Frame Ins(6)/Del(4)
|
6.27 × 10-13c
|
1.18 × 10−8
|
RCC [23], ESCC [24]
|
|
TMPRSS13
|
11
|
In Frame Del(6), Missense(5)
|
1.40 × 10-10c
|
1.32 × 10−6
| |
|
KRTAP4-5
|
17
|
In Frame Ins(5), Missense(1)
|
5.07 × 10-8c
|
3.19 × 10−4
| |
|
OR2T35
|
1
|
Frame Shift Ins(1)/Del(4)
|
1.50 × 10-7c
|
7.09 × 10−4
| |
|
HAVCR1
|
5
|
Intron SNV(1), In Frame Del(5), Silent(1)
|
3.62 × 10-7c
|
1.37 × 10−3
|
Colorectal [25], RCC [26]
|
|
IFI27
|
14
|
In Frame Ins(3)
|
6.88 × 10-6c
|
0.02
|
Ovarian [27], Breast [28]
|
|
PCSK5
|
9
|
Intron SNV(1), Frame Shift Del(6), 3′UTR Ins(7)/Del(1)
|
8.50 × 10-6c
|
0.02
|
Lung [29]
|
|
GPRIN1
|
5
|
Missense(1), In Frame Del(5)
|
8.88 × 10-6c
|
0.02
| |
|
MRPL18
|
6
|
In Frame Del(3)
|
2.09 × 10−5
|
0.04
| |
|
ARSD
|
X
|
Intron Ins(2)/Del(2), In Frame Del(4)
|
2.93 × 10−5
|
0.05
|
CLL [30]
|
|
MAML3
|
4
|
In Frame Ins(2)/Del(4), Silent(3), Intron Del(1)
|
3.33 × 10−5
|
0.05
| |
|
AML-M2 (p < 0.01)
|
|
CEBPA
|
19
|
In Frame Ins(3)
|
5.22 × 10−5
|
0.49
|
HCC [31], AML [32]
|
|
EP400
|
12
|
Intron Del(1), In Frame Ins(4)/Del(1)
|
3.45 × 10−4
|
1
|
RCC [33], Colorectal [34]
|
|
AML-M3 (p < 0.01)
|
|
ATXN3
|
14
|
In Frame Ins(2), Intron Ins(1)
|
9.75 × 10−4
|
1
|
Lung [35]
|
