Fig. 2From: Mutation affecting the proximal promoter of Endoglin as the origin of hereditary hemorrhagic telangiectasia type 1Histograms representing the relative luciferase activity of wild type and mutated Endoglin promoter reporters after transfection into endothelial HMEC-1 cells. Site-directed mutagenesis was performed on the wild type promoter/reporter plasmid (350/+350 CD105 pXP2) of Endoglin. The effect of TGF-β treatment is also shownBack to article page