Table 1 Number of polymorphisms detected in the promotor regions of the TLR1-TLR10 genes. Promoter region is for both populations defined as 50 bp downstream and 500 bp upstream of the start of exon 1. The AR population contains 288 individuals and the EUR population contains 379 individuals
From: Genetic variation of the Toll-like receptors in a Swedish allergic rhinitis case population
AR population | EUR population | |||||
|---|---|---|---|---|---|---|
Gene | Total | ≤1%a | AR-specificb | Total | ≤ 1%a | EUR-specificc |
TLR1 | 5 | 1 | 1 | 4 | 0 | 0 |
TLR2 | 3 | 1 | 0 | 6 | 3 | 3 |
TLR3 | 4 | 3 | 3 | 1 | 1 | 0 |
TLR4 | 0 | 0 | 0 | 2 | 2 | 2 |
TLR5 | 2 | 0 | 0 | 4 | 2 | 2 |
TLR6 | 5 | 1 | 1 | 9 | 4 | 5 |
TLR7 | 1 | 1 | 1 | 2 | 1 | 2 |
TLR8 | 2 | 0 | 0 | 3 | 1 | 1 |
TLR9 | 2 | 1 | 2 | 2 | 1 | 2 |
TLR10 | 13 | 6 | 6 | 7 | 0 | 0 |
Total | 37 | 14 | 14 | 40 | 15 | 17 |