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Table 1 Evolutionary conservation analysis of the novel m.15933G > A mutation in MTTT among mammals

From: A novel MTTT mutation m.15933G > A revealed in analysis of mitochondrial DNA in patients with suspected mitochondrial disease

 

T-stem

T-loop

Patient 41

49 CTTT

65 AAAA

ACCTT

Homo sapiens

49 CTTT

65 GAAA

ACCTT

Pan paniscus

49 CTTA

65 GAAA

ACTTT

Pan trogdolytes

49 CTTC

65 GAAA

ACTTT

Gorilla gorilla

49 CTTC

65 GAAG

ACCTC

Hylobates lar

49 CTTC

65 GAAA

TCTTC

Rattus norwegicus

49 CTTC

65 GAAG

AGTCT

Mus musculus

49 CTTC

65 GAAG

ATCTT

Bos taurus

49 CCTC

65 GGAG

AACAC

  1. Mammalian MTTT sequences covering the T-stem base pairs and the T-loop. The nucleotide position m.15933 in consensus position 49 and its pair in position 65 are shown in the superscripts and the nucleotides are underlined